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KMID : 0613320090150010052
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Journal of the Korean Bone and Joint Tumor Soceity
2009 Volume.15 No. 1 p.52 ~ p.58
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Giant Cell Tumor of the Rib: A Case Report and Review of the Literature
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Kim Hyun-Soo
Kim Dae-Hyun
Lim Sung-Jig
Park Yong-Ku
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Abstract
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Giant cell tumor (GCT) of the rib may present as a posterior mediastinal mass when it involves the posterior arc. Only 4 cases of GCT of the rib presenting as a posterior mediastinal mass have been reported. We report a case of a 38-year-old man with GCT of the rib. Computed tomography revealed a well-defined, multi-lobulated, heterogeneous mass in the right superoposterior mediastinum, which appeared to invade the right third rib and thoracic vertebra. It was thought to be a posterior mediastinal ganglioneuroma or its malignant transformation. Grossly, the tumor mass arose in the posterior arc and showed substantial growth out of the rib. Microscopically, the tumor consisted of interspersed multi-nucleated giant cells and stromal mononuclear cells, compatible with GCT. For GCT, a wide excision with elective radiotherapy should be considered. GCT must be differentiated from posterior mediastinal ganglioneuroma that can be treated by surgical excision alone.
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KEYWORD
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Rib, Giant cell tumor, Ganglioneuroma
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